Table of Contents

October 01, 2026; Volume 93, Issue 10
  • From the Editor

  • The Clinical Picture

  • 1-Minute Consult

      • How can I differentiate delirium from altered mental status in hospitalized older adults?

        Asim Kichloo, MD, Calista Hemarga, BS, Ivan Magallanes Marrufo, MPH and Sandra Davis, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 581-585;
        • DOI: https://doi.org/10.3949/ccjm.93a.26025
        • Bedside screening tools can be used to distinguish delirium from other causes of altered mental status, enabling timely care and reducing costs.

      • How should I evaluate allergic disease in patients with asthma?

        Alejandro Chapa-Rodriguez, MD and Jennifer Tartaglia, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 586-588;
        • DOI: https://doi.org/10.3949/ccjm.93a.25119
        • Indiscriminate testing can lead to misinterpretation of results, unnecessary escalation of therapy, and increased cost without clinical benefit.

  • Editorial

      • Immunoglobulin E: From horses to myeloma

        Adam J. Brown, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 589-591;
        • DOI: https://doi.org/10.3949/ccjm.93a.26078
        • The author explores how IgE was discovered, the challenges researchers faced when isolating the antibody, and the connection among IgE, mast cells, and histamine.

  • Symptoms to Diagnosis

      • Acute vertigo in a 67-year-old woman: Peripheral or central?

        David Kweku Aseda Donkor, MD, Kapil Nayar, MD and Jerma Adams, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 592-596;
        • DOI: https://doi.org/10.3949/ccjm.93a.26035
        • The patient presented with dizziness that started earlier that morning when she rose from bed, persisted after she returned to bed, and worsened with head movement.

  • Interpreting Key Trials

  • Guidelines to Practice

      • Peripheral artery disease: Putting the updated 2024 AHA/ACC guideline into practice

        CME Image
        Pavel Kibrik, DO, Enrico Prajiante Bertolino, MD, Sasan Partovi, MD, G. Jay Bishop, MD, Aravinda Nanjundappa, MD and Lee Kirksey, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 603-615;
        • DOI: https://doi.org/10.3949/ccjm.93a.25101
        • The new guideline, which updates the 2016 guideline, clarifies clinical terminology, applies trial evidence to pharmacotherapy and revascularization recommendations, and addresses equity and access to care.

  • Review

      • TOC Icon

        Shedding: An updated guide to a common cause of hair loss

        Wilma F. Bergfeld, MD and Daniela Mendez, MD
        • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 616-622;
        • DOI: https://doi.org/10.3949/ccjm.93a.26008
        • Telogen effluvium, or hair shedding, results from a temporary disruption of the normal hair growth cycle and typically is reversible.

  • Corrections