Table of Contents

It would be nice to have a treatment option for pain that is less limited by side effects, cognitive dysfunction, addiction potential, and red tape.

The patient had a history of type 2 diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia, with a fasting serum triglyceride level of 9,000 mg/dL.

Given the wide availability of direct-to-consumer laboratory testing, it is reasonable to ask whether a working knowledge of xanthomas still matters for trainees and clinicians.

Potassium-competitive acid blockers are reserved for patients who cannot tolerate proton pump inhibitors or who do not respond to them.

Clinicians in the primary care setting can identify patients with heavy alcohol use and alcohol-related liver disease before they develop advanced liver damage.

The systemic sodium channel blocker suzetrigine may serve as another option for multimodal postoperative analgesia regimens and for managing acute nonsurgical pain.

The patient presented to the emergency department due to worsening dry cough, lower-extremity edema, and fatigue, all of which had begun about 2 weeks earlier.

The patient initially experienced dyspnea only on exertion, but over the 2 months before presentation it had progressed to shortness of breath at rest.

Using practical clinical examples, the authors explain the subset of artificial intelligence called large language models, highlighting the capabilities and limitations of these systems.