More articles from Current Drug Therapy

  • Potassium-competitive acid blockers: Clinical pearls and practical insights

    Hisham Wehbe, MD and Claire Beveridge, MD
    • Cleveland Clinic Journal of Medicine June 2026, 93 (6) 341-346;
    • DOI: https://doi.org/10.3949/ccjm.93a.25070

    • P-CABs provide rapid, potent, predictable acid suppression without the need for timing around meals, but their current role is focused and limited.

  • Update on antiobesity pharmacotherapy in adults: Current and emerging options

    Farah Ziyadeh, MD, Sara Saliba, MD, RD, Dania Salih Bacha, MD, Yael Mauer, MD, MPH, Marcio L. Griebeler, MD, DABOM and Bartolome Burguera, MD, PhD
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 36-46;
    • DOI: https://doi.org/10.3949/ccjm.93a.24112

    • The authors review antiobesity medications that are currently available or under investigation and discuss how to personalize obesity treatment.

  • Reducing the risks when using benzodiazepines to treat insomnia: A public health approach

    Vania Modesto-Lowe, MD, MPH, Margaret M. Chaplin, MD, Roberto León-Barriera, MD and Lakshit Jain, MD
    • Cleveland Clinic Journal of Medicine May 2024, 91 (5) 293-299;
    • DOI: https://doi.org/10.3949/ccjm.91a.23061

    • The authors review measures for preventing harm before benzodiazepines are prescribed, decreasing harm within 4 weeks after they are prescribed, and limiting harmful effects of long-term prescribing.

  • Nonstatin therapy to reduce low-density lipoprotein cholesterol and improve cardiovascular outcomes

    Abhayjit Singh, MD and Leslie S. Cho, MD
    • Cleveland Clinic Journal of Medicine January 2024, 91 (1) 53-63;
    • DOI: https://doi.org/10.3949/ccjm.91a.23058

    • Several new nonstatin medications have been approved in recent years, with robust data from clinical trials supporting their use in atherosclerotic disease.

  • A practical guide for buprenorphine initiation in the primary care setting

    Roberto León-Barriera, MD, Samantha Jayne Zwiebel, MD, MA and Vania Modesto-Lowe, MD, MPH
    • Cleveland Clinic Journal of Medicine September 2023, 90 (9) 557-564;
    • DOI: https://doi.org/10.3949/ccjm.90a.23022

    • The authors review changes in prescribing laws and outline buprenorphine induction protocols that can be adopted in the primary care setting.

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    Update on current contraceptive options: A case-based discussion of efficacy, eligibility, and use

    Alexa Nicole Fiffick, DO, MBS, NCMP, Tara K. Iyer, MD, NCMP, Tiffany Cochran, MD, MA, NCMP and Pelin Batur, MD, FACP, NCMP
    • Cleveland Clinic Journal of Medicine March 2023, 90 (3) 181-190;
    • DOI: https://doi.org/10.3949/ccjm.90a.22075

    • Rates of unintended pregnancy are high in the United States. Clinicians need to be well-informed about the full spectrum of contraceptive options to improve reproductive autonomy.

  • Antiobesity drug therapy: An individualized and comprehensive approach

    Yael Mauer, MD, MPH, Marcie Parker, PharmD, BCACP and Sangeeta R. Kashyap, MD
    • Cleveland Clinic Journal of Medicine August 2021, 88 (8) 440-448;
    • DOI: https://doi.org/10.3949/ccjm.88a.20080

    • As part of a comprehensive plan, these drugs can provide lasting obesity control and additional health benefits, including decreased cardiovascular risk.

  • Prescribing testosterone and DHEA: The role of androgens in women

    Taryn Smith, MD, NCMP and Pelin Batur, MD, FACP, NCMP
    • Cleveland Clinic Journal of Medicine January 2021, 88 (1) 35-43;
    • DOI: https://doi.org/10.3949/ccjm.88a.20030

    • Androgens play an important physiologic role and can promote sexual health.

  • The role of SGLT-2 inhibitors in managing type 2 diabetes

    Yumiko Tsushima, MD, M. Cecilia Lansang, MD, MPH and Vinni Makin, MBBS, MD, FACE
    • Cleveland Clinic Journal of Medicine January 2021, 88 (1) 47-58;
    • DOI: https://doi.org/10.3949/ccjm.88a.20088

    • These drugs improve glycemic control and offer cardiovascular and metabolic benefits.

  • CGRP antagonists for decreasing migraine frequency: New options, long overdue

    Julia Bucklan, DO and Zubair Ahmed, MD
    • Cleveland Clinic Journal of Medicine April 2020, 87 (4) 211-218;
    • DOI: https://doi.org/10.3949/ccjm.87a.19048

    • CGRP drugs are an exciting frontier, but migraine management is still a combination of lifestyle changes plus treatment.

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