Emergency Medicine

  • Kratom at a crossroads: Trends, controversies, and the evidence gap

    Vania Modesto-Lowe, MD, MPH, Deanna Sgambato, DMS, MHS, PA-C, Jasleen Kaur, MD and Margaret Chaplin, MD
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 487-492;
    • DOI: https://doi.org/10.3949/ccjm.93a.25088

    • Amid the opioid crisis, kratom use has grown for self-management of pain, mood symptoms, and opioid withdrawal.

  • Digoxin is still useful, but is still causing toxicity

    Alejandro Durán Crane, MD, Michael Militello, PharmD, BCPS and Michael D. Faulx, MD
    • Cleveland Clinic Journal of Medicine August 2024, 91 (8) 489-499;
    • DOI: https://doi.org/10.3949/ccjm.91a.23105

    • The authors review the presentation of digoxin toxicity, its mechanisms and predisposing factors, and its medical management.

  • Foxglove, not quite gone or forgotten

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine August 2024, 91 (8) 458-459;
    • DOI: https://doi.org/10.3949/ccjm.91b.08024

    • Digoxin use has waned dramatically over the past decades, with good reason, but for select patients, it may be a very reasonable option.

  • Should you use compression duplex ultrasonography to detect deep vein thrombosis to evaluate unexplained fevers?

    Daniel Rozenbaum, MD, Anirudh Yalamanchali, MD, MS and Deborah Hornacek, MD, FSVM
    • Cleveland Clinic Journal of Medicine October 2023, 90 (10) 611-614;
    • DOI: https://doi.org/10.3949/ccjm.90a.23018

    • The authors provide recommendations on when to order imaging of the extremities in the evaluation of hospitalized patients with unexplained fever.

  • Evaluating troponin elevation in patients with chronic kidney disease and suspected acute coronary syndrome

    Lorenzo Braghieri, MD, Osamah Z. Badwan, MD, Warren Skoza, MD, Maan Fares, MD and Venu Menon, MD
    • Cleveland Clinic Journal of Medicine August 2023, 90 (8) 483-489;
    • DOI: https://doi.org/10.3949/ccjm.90a.23012

    • The authors examine challenges in diagnosing acute coronary syndrome in patients with chronic kidney disease and provide a diagnostic algorithm to risk-stratify these patients.

  • Severe skin rashes

    Li-wen Zhang, MD, Juan Wu, MD, PhD and Tao Chen, MD, PhD
    • Cleveland Clinic Journal of Medicine August 2023, 90 (8) 461-462;
    • DOI: https://doi.org/10.3949/ccjm.90c.08003

  • In Reply: Severe skin rashes

    Valerie Jaroenpuntaruk, MD and Adam Gray, MD
    • Cleveland Clinic Journal of Medicine August 2023, 90 (8) 462;
    • DOI: https://doi.org/10.3949/ccjm.90c.08004

  • Acute left-sided colonic diverticulitis: A surgeon’s perspective on the ACP guidelines

    Michael J. Klingler, MD, MS and Jeremy M. Lipman, MD, MHPE
    • Cleveland Clinic Journal of Medicine July 2023, 90 (7) 403-406;
    • DOI: https://doi.org/10.3949/ccjm.90a.22050

    • The updated guidelines push for less-aggressive management of uncomplicated diverticulitis in select patients.

  • Deadly drug rashes: Early recognition and multidisciplinary care

    Valerie Jaroenpuntaruk, MD and Adam Gray, MD
    • Cleveland Clinic Journal of Medicine June 2023, 90 (6) 373-381;
    • DOI: https://doi.org/10.3949/ccjm.90a.22043

    • An illustrated review of 4 severe drug rashes. Early recognition and prompt withdrawal of the causative agent are crucial.

  • What is the optimal approach to infiltration and extravasation of nonchemotherapy medications?

    Abby Tarpey, PharmD, Shraddha Narechania, MD, FCCP and Mark Malesker, PharmD, FCCP, FCCM, FASHP, BCPS
    • Cleveland Clinic Journal of Medicine May 2023, 90 (5) 292-296;
    • DOI: https://doi.org/10.3949/ccjm.90a.22029

    • The immediate response is warm or cold compression and assessment of the severity.

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