Nephrology

In Reply: Diagnostic challenges in gastrointestinal calciphylaxis
Brennan Gioe, MD, Conrad Fernandes, MD, E. Celia Marginean, MD and Stalin Subramanian, MD
- Cleveland Clinic Journal of Medicine September 2026, 93 (9) 507-508;
- DOI: https://doi.org/10.3949/ccjm.93c.09002
Primary aldosteronism: Interpreting the 2025 Endocrine Society clinical practice guideline update
Nandhini Bindukumari Sureshkumar, MD, Marguerite O. Linz, MD, Pratibha PR Rao, MD, MPH and Ricardo Correa, MD, EdD
- Cleveland Clinic Journal of Medicine September 2026, 93 (9) 515-522;
- DOI: https://doi.org/10.3949/ccjm.93a.25107
- The new guideline agrees with growing evidence that primary aldosteronism is common, often missed, and treatable.
New guidance on primary aldosteronism: Rethinking screening in hypertension
George Thomas, MD
- Cleveland Clinic Journal of Medicine September 2026, 93 (9) 525-526;
- DOI: https://doi.org/10.3949/ccjm.93a.26073
- The 2025 Endocrine Society guideline is best viewed not as the final word on primary aldosteronism, but as the beginning of an important conversation.
Letter: Diagnostic challenges in gastrointestinal calciphylaxis
Sadeem Muhammad Rizwan, MBBS
- Cleveland Clinic Journal of Medicine September 2026, 93 (9) 507;
- DOI: https://doi.org/10.3949/ccjm.93c.09001
Iatrogenic calcinosis cutis from calcium gluconate extravasation
Fotios Vlahos, MS and Iosifina Giannakikou, MD
- Cleveland Clinic Journal of Medicine August 2026, 93 (8) 454-456;
- DOI: https://doi.org/10.3949/ccjm.93a.25112
- While receiving an infusion of 10% calcium gluconate, the patient developed pain, swelling, and erythema at the catheter site.
KDIGO chronic kidney disease heat map: Let the colors be your guide!
Crystal Gadegbeku, MD
- Cleveland Clinic Journal of Medicine June 2026, 93 (6) 366-367;
- DOI: https://doi.org/10.3949/ccjm.93a.26017
- Clinicians need to adopt early interventions that can alter the course of chronic kidney disease for patients.
Managing chronic kidney disease according to KDIGO risk categories: A primer for primary care
Rodolfo J. Galindo, MD, Diana Soliman, MD, Joshua J. Neumiller, PharmD, Jay H. Shubrook, DO and Katherine R. Tuttle, MD
- Cleveland Clinic Journal of Medicine June 2026, 93 (6) 353-365;
- DOI: https://doi.org/10.3949/ccjm.93a.25072
- The authors review the KDIGO guideline updates and provide a simplified treatment algorithm for non-nephrologists, focusing on medication sequencing and monitoring.
Hematochezia in a patient with end-stage renal disease
Brennan Gioe, MD, Conrad Fernandes, MD, E. Celia Marginean, MD and Stalin Subramanian, MD
- Cleveland Clinic Journal of Medicine June 2026, 93 (6) 333-338;
- DOI: https://doi.org/10.3949/ccjm.93a.25097
- The patient developed gastrointestinal bleeding after being started on intravenous heparin following thrombectomy and angioplasty for acute limb ischemia.
Finding the cause of severe hypokalemia
Philip S. Mehler, MD and Dennis Gibson, MD
- Cleveland Clinic Journal of Medicine April 2026, 93 (4) 198;
- DOI: https://doi.org/10.3949/ccjm.93c.04001
In Reply: Finding the cause of severe hypokalemia
Enmanuel A. Leiva-Murillo, MD, Erwin Bechtold-Javier, MD, Pol Candela-Parrilla, MD and Ana Matas-García, MD, PhD
- Cleveland Clinic Journal of Medicine April 2026, 93 (4) 198;
- DOI: https://doi.org/10.3949/ccjm.93c.04002