Rheumatology

  • Painless sternoclavicular osteitis in fever of unknown origin: A clue to probable SAPHO syndrome

    Taisuke Kamiyoshikawa, MD, Kensaku Shojima, MD, PhD, Yoshihiro Wada, MD, PhD, Hiromitsu Yamazaki, MD, PhD, Yasuyuki Nagasawa, MD, PhD and Ken Shinmura, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 578-580;
    • DOI: https://doi.org/10.3949/ccjm.93a.25110

    • After more than 1 month of acetaminophen, the patient continued to have fever and elevated inflammatory markers.

  • Sclerotic lesions in the metadiaphysis regions of the knee

    Alyssa Hill, MD and Morteza Khodaee, MD, MPH
    • Cleveland Clinic Journal of Medicine July 2026, 93 (7) 383-385;
    • DOI: https://doi.org/10.3949/ccjm.93a.25071

    • The patient presented with left knee pain located over her patella that had progressively worsened over 4 months.

  • Localized dead bone, a potential hint to an underlying condition

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine July 2026, 93 (7) 375-376;
    • DOI: https://doi.org/10.3949/ccjm.93b.07026

    • The discovery of osteonecrosis by imaging, whether the patient is symptomatic or not, warrants consideration for the presence of an underlying condition.

  • Complement inhibition: A whole new world

    Nicholas Salupo, DO, Korey Bartolomeo, DO, Elias Bassil, MD, Corey Cavanaugh, DO, Georges Nakhoul, MD, MEd, Jonathan Taliercio, DO and Ali Mehdi, MD, MEd
    • Cleveland Clinic Journal of Medicine April 2026, 93 (4) 227-236;
    • DOI: https://doi.org/10.3949/ccjm.93a.25076

    • As these medications enter the mainstream, understanding the complement system and the benefits and risks of therapeutic blockade has become crucial for optimal patient care.

  • Clinical application of the complement system: A historical perspective

    Adam J. Brown, MD
    • Cleveland Clinic Journal of Medicine April 2026, 93 (4) 237-239;
    • DOI: https://doi.org/10.3949/ccjm.93a.26014

    • Now that our understanding of complement has evolved to therapeutic targeting of components of the cascade in a wide range of diseases, it is time to give the complement system another look.

  • ‘Boxing glove’ hands in a patient initially diagnosed with RS3PE syndrome

    Hirokazu Takai, MD and Seiko Takai, MD
    • Cleveland Clinic Journal of Medicine March 2026, 93 (3) 135-137;
    • DOI: https://doi.org/10.3949/ccjm.93a.25059

    • The patient had edema that limited finger flexion, impairing daily tasks such as putting on socks.

  • Multicentric reticulohistiocytosis

    Atul Khasnis, MD, MS and Joseph M. Dyer, DO
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 9-11;
    • DOI: https://doi.org/10.3949/ccjm.93a.24124

    • A 58-year-old man presented with a 2-month history of joint pain and swelling and a rash.

  • What is the optimal time for bone density screening in patients with premature ovarian insufficiency?

    Dewonna Ferguson, MD, MSCP, Suneela Vegunta, MD, MSCP and Sara Shihab, MD, MSCP
    • Cleveland Clinic Journal of Medicine November 2025, 92 (11) 676-678;
    • DOI: https://doi.org/10.3949/ccjm.92a.24116

    • Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.

  • Collaborative musculoskeletal care: The role for chiropractors

    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 593;

  • MDA5 dermatomyositis: Unveiling a potentially life-threatening disease

    Soumya Chatterjee, MD, MS
    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 627-637;
    • DOI: https://doi.org/10.3949/ccjm.92a.25018

    • Timely diagnosis and initiation of aggressive immunosuppressive therapy are key to improving the 40% overall mortality rate in patients with MDA5 dermatomyositis.

Previous
Next