Locally advanced non–small cell lung cancer: What is the optimal concurrent chemoradiation regimen?

  • Cleveland Clinic Journal of Medicine
  • May 2012,
  • 79
  • (5 e-suppl 1)
  • S32-S37;
  • DOI: https://doi.org/10.3949/ccjm.79.s2.07

ABSTRACT

The optimal chemoradiation regimen for patients with locally advanced non–small cell lung cancer (NSCLC) has yet to be defined. Disease and patient heterogeneity prevent a “one size fits all” approach to treatment. Concurrent chemoradiation up front is the definitive strategy for patients with unresectable stage III NSCLC; the addition of consolidation chemotherapy following definitive treatment has produced conflicting results with respect to overall survival. Biologic therapies have yet to show value as add-on treatment to chemoradiation.

Footnotes

  • Dr. Videtic reported that he has no financial relationships that pose a potential conflict of interest with this article.

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